Background Materials

The following links may be of interest as background material.

Plotkin S.A., Orenstein W.A. (eds.), Vaccines (Fourth Edition), published by Saunders Press (Philadelphia, PA), 2004. pp. 1283 – 1289.

"Malaria Vaccine" (MS Word 375 KB)

The Lancet, Volume 363, published Jan 2004

"Malaria Vaccine Developments" (PDF 180 KB) Download Acrobat Reader
Reprinted with permission from Elsevier (The Lancet, 2004, Volume 363, pp 150-156)

Malaria Vaccine Initiative Technical Series, published Aug 2004

"Clinical Trials: Crucial Steps on the Road to a Malaria Vaccine" (PDF 227 KB) Download Acrobat Reader

World Health Organization, Initiative for Vaccine Research (IVR), published July 2004

"Portfolio of candidate malaria vaccines currently in development" (PDF 311 KB) Download Acrobat Reader

Nature Outlook Malaria supplement, published Aug 19, 2004

"Malaria: The long road to a healthy Africa"

Nature Outlook's Malaria supplement zeroes in on the major issues in the war on malaria, with a particular focus on Africa. It analyzes the current state of affairs, the major obstacles to treatment and control, and the areas that present promising opportunities for progress. Read the supplement.

The supplement includes several articles that mention malaria vaccines, specifically:

Strength in Unity
Save the Children
An Attack on all Fronts

American Journal of Tropical Medicine and Hygiene Malaria Supplement, published Sep 9, 2004

"The Intolerable Burden of Malaria II: What's New What's Needed"

Featured papers in this malaria supplement discuss the latest findings on relationships between malaria and other morbidities, including HIV in pregnant women; malnutrition; and neurological, cognitive, and development sequelae. The authors explore new antimalaria treatment methods, examine methods for calculating the global burden of disease and malaria, and assess the impact of mosquito transmission on morbidity and mortality. Approaches for determining the economic toll caused by malaria are examined and the role of urban malaria, epidemics and social and economic burdens in impeding the development of newer, more cost-effective malaria control methods are analyzed. Featured papers also discuss the research agenda and activities that help to define malaria's toll on the world's population. Read the supplement.

Papers of particular interest in this AJTMH supplement include the following:

Updates on the Clinical Development of Candidate Malaria Vaccines
Policy Challenges in Malaria Vaccine Introduction